January
01 – birth of Luise of Saxe-Gotha-Altenburg, wife of Grand Duke Friedrich Franz I (1756)
01 – death of Luise of Saxe-Gotha-Altenburg, wife of Grand Duke Friedrich Franz I (1808)
04 – death of Luise Charlotte, Hereditary Princess of Saxe-Gotha-Altenburg, dtr of Friedrich Franz I (1801)
10 – death of Gustav Wilhelm, son of Grand Duke Friedrich Franz I (1851)
23 – death of Nikolaus, son of Grand Duke Friedrich Franz II (1856)
24 – marriage of Grand Duke Friedrich Franz III to Anastasia Mikhailovna of Russia (1879)
25 – death of Anastasia, daughter of Grand Duke Friedrich Franz IV (1979)
29 – birth of Marie of Schwarzburg-Rudolstadt, 3rd wife of Grand Duke Friedrich Franz II (1850)
31 – birth of Gustav Wilhelm, son of Grand Duke Friedrich Franz I (1781)

February
01 – death of Grand Duke Friedrich Franz I (1837)
04 – death of Olga, daughter of Grand Duke Friedrich Franz IV (1917)
08 – death of Anne, daughter of Grand Duke Friedrich Franz II (1882)
16 – death of Johann Albrecht, son of Grand Duke Friedrich Franz II (1920)
23 – birth of Alexandrine of Prussia, wife of Grand Duke Paul Friedrich (1803)
28 – birth of Grand Duke Friedrich Franz II (1823)

March
03 – death of Grand Duchess Auguste, 1st wife of Grand Duke Friedrich Franz II (1862)
05 – birth of Wilhelm, son of Grand Duke Paul Friedrich (1827)
07 – death of Grand Duke Paul Friedrich (1842)
09 – death of Luise of Windisch-Grätz, daughter of Grand Duke Paul Friedrich (1859)
11 – death of Grand Duchess Anastasia, wife of Grand Duke Friedrich Franz III (1922)
19 – birth of Grand Duke Friedrich Franz III (1851)

April
05 – birth of Friedrich Wilhelm, son of Grand Duke Friedrich Franz II (1871)
07 – birth of Anne, daughter of Grand Duke Friedrich Franz II (1865)
09 – birth of Grand Duke Friedrich Franz IV (1882)
10 – death of Grand Duke Friedrich Franz III (1897)
15 – death of Grand Duke Friedrich Franz II (1883)
16 – death of Grand Duchess Anna, 2nd wife of Grand Duke Friedrich Franz II (1865)
19 – birth of Heinrich, son of Grand Duke Friedrich Franz II (1876)
21 – death of Grand Duchess Alexandrine, wife of Grand Duke Paul Friedrich (1892)
22 – birth of Hereditary Grand Duke Friedrich Franz, son of Grand Duke Friedrich Franz IV (1910)
22 – death of Grand Duchess Marie, 3rd wife of Grand Duke Friedrich Franz II (1922)

May
06 – death of German Crown Princess Cecilie, daughter of Grand Duke Friedrich Franz III (1954)
14 – birth of Marie, daughter of Grand Duke Friedrich Franz II (1854)
17 – birth of Luise, daughter of Grand Duke Paul Friedrich (1824)
17 – death of Paul Friedrich, son of Grand Duke Friedrich Franz II (1923)
22 – death of Karl, son of Grand Duke Friedrich Franz I (1833)
25 – marriage of Grand Duke Paul Friedrich to Alexandrine of Prussia (1822)
25 – birth of Anna of Hesse and by Rhine, 2nd wife of Grand Duke Friedrich Franz II (1843)
26 – birth of Auguste Reuss of Köstritz, 1st wife of Grand Duke Friedrich Franz II (1822)

June
01 – marriage of Grand Duke Friedrich Franz I to Luise of Saxe-Gotha-Altenburg (1775)
07 – marriage of Grand Duke Friedrich Franz IV to Alexandra of Hanover and Cumberland (1904)
13 – birth of Hereditary Grand Duke Friedrich Ludwig, son of Grand Duke Friedrich Franz I (1778)
17 – Establishment of the Grand Duchy of Mecklenburg-Schwerin (1815)
18 – birth of Thyra, daughter of Grand Duke Friedrich Franz IV (1919)

July
02 – birth of Karl, son of Grand Duke Friedrich Franz I (1782)
03 – death of Henrik, Prince Consort of the Netherlands, son of Friedrich Franz II (1934)
04 – marriage(2) of Grand Duke Friedrich Franz II to Anna of Hesse and by Rhine (1864)
04 – marriage(3) of Grand Duke Friedrich Franz II to Marie of Schwarzburg-Rudolstadt (1868)
13 – death of Charlotte Friederike, Hereditary Princess of Denmark, dtr of Friedrich Franz I (1840)
18 – Christian Ludwig, son of Grand Duke Friedrich Franz IV (1996)
28 – birth of Anastasia Mikhailovna of Russia, wife of Grand Duke Friedrich Franz III (1860)
28 – death of Wilhelm, son of Grand Duke Paul Friedrich (1879)
31 – death of Hereditary Grand Duke Friedrich Franz, son of Grand Duke Friedrich Franz IV (2001)

August
05 – death of Adolf Friedrich, son of Grand Duke Friedrich Franz II (1969)
10 – birth of Elisabeth Alexandrine, daughter of Grand Duke Friedrich Franz II (1869)
13 – birth and death of Alexander, son of Grand Duke Friedrich Franz II (1859)
18 – birth of Nikolaus, son of Grand Duke Friedrich Franz II (1855)
30 – death of Grand Duchess Alexandra, wife of Grand Duke Friedrich Franz IV (1963)

September
03 – death of Grand Duchess Elisabeth Alexandrine of Oldenburg, daughter of Friedrich Franz II (1955)
06 – death of Grand Duchess Maria Pavlovna of Russia, daughter of Friedrich Franz II (1920)
15 – birth of Grand Duke Paul Friedrich (1800)
19 – birth of Paul Friedrich, son of Grand Duke Friedrich Franz II (1852)
20 – birth of Cecilie, daughter of Grand Duke Friedrich Franz III (1886)
22 – death of Friedrich Wilhelm, son of Grand Duke Friedrich Franz II (1897)
24 – death of Hered. Grand Duchess Elena Pavlovna, wife of Friedrich Ludwig (1803)
27 – death of Thyra, daughter of Grand Duke Friedrich Franz IV (1981)
29 – birth of Alexandra of Hanover and Cumberland, wife of Grand Duke Friedrich Franz IV (1882)
29 – birth of Christian Ludwig, son of Grand Duke Friedrich Franz IV (1912)

October
10 – birth of Adolf Friedrich, son of Grand Duke Friedrich Franz II (1873)
12 – marriage of Hered. Grand Duke Friedrich Ludwig to Elena Pavlovna of Russia (1799)

November
01 – marriage(1) of Grand Duke Friedrich Franz II to Auguste Reuss of Köstritz (1849)
11 – birth of Anastasia, daughter of Grand Duke Friedrich Franz IV (1922)
14 – abdication of Grand Duke Friedrich Franz IV and end of the monarchy of Mecklenburg-Schwerin (1918)
17 – death of Grand Duke Friedrich Franz IV (1945)
19 – birth of Luise Charlotte, daughter of Grand Duke Friedrich Franz I (1779)
29 – death of Hereditary Grand Duke Friedrich Ludwig, son of Grand Duke Friedrich Franz I (1819)

December
04 – birth of Charlotte Friederike, daughter of Grand Duke Friedrich Franz I (1784)
08 – birth of Johann Albrecht, son of Grand Duke Friedrich Franz II (1857)
10 – birth of Grand Duke Friedrich Franz I (1756)
24 – birth of Elena Pavlovna of Russia, wife of Hered. Grand Duke Friedrich Ludwig (1784)
24 – birth of Alexandrine, daughter of Grand Duke Friedrich Franz III (1879)
27 – birth of Olga, daughter of Grand Duke Friedrich Franz IV (1916)
28 – death of Queen Alexandrine of Denmark, daughter of Friedrich Franz III (1952)